Speaker 3: Anissa Abi-Dargham, USA
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منابع مشابه
PET imaging of dopamine-D2 receptor internalization in schizophrenia
This corrects the article DOI: 10.1038/mp.2017.107.
متن کاملPresynaptic regulation of dopamine transmission in schizophrenia.
A role for dopamine (DA) release in the hallucinations and other positive symptoms associated with schizophrenia has long been inferred from the antipsychotic response to D2 DA receptor antagonists and because the DA releaser amphetamine can be psychotogenic. Recent studies suggest that patients with schizophrenia, including those never exposed to antipsychotic drugs, maintain high presynaptic ...
متن کاملNeurobiology of dopamine in schizophrenia.
This chapter is an update on the dopamine (DA) imbalance in schizophrenia, including the evidence for subcortical hyperstimulation of D2 receptors underlying positive symptoms and cortical hypodopaminergia-mediating cognitive disturbances and negative symptoms. After a brief review of the anatomical neurocircuitry of this transmitter system as a background, we summarize the evidence for dopamin...
متن کاملHow have developments in molecular imaging techniques furthered schizophrenia research?
Molecular imaging techniques have led to significant advances in understanding the pathophysiology of schizophrenia and contributed to knowledge regarding potential mechanisms of action of the drugs used to treat this illness. The aim of this article is to provide a review of the major findings related to the application of molecular imaging techniques that have furthered schizophrenia research...
متن کاملRecent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia.
Wayne Fenton was a major driving force behind the establishment of the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) and Treatment Units for Research on Neurocognition and Schizophrenia (TURNS) project mechanisms. These projects were designed to facilitate the development of new drugs for the treatment of cognitive impairments in people with schizophrenia. T...
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عنوان ژورنال:
دوره 19 شماره
صفحات -
تاریخ انتشار 2016